Board Justification

We review compensation annually for all employees, including our named executive officers. In setting executive base salaries and bonuses and granting equity incentive awards, we consider compensation for comparable positions in the market, the historical compensation levels of our executives, individual performance as compared to our expectations and objectives, our desire to motivate our employees to achieve short- and long-term results that are in the best interests of our stockholders and a long-term commitment to our company.

Board Justification

The amounts in this column represent the discretionary annual cash bonus paid with respect to the applicable year. For her 2022 performance, Dr. Shendelman received a bonus payable in equal parts cash and RSUs vested in full as of the date of grant. A total of $225,000 of this bonus was payable in cash, 50% of which was paid in January 2023 and 50% of which was paid in June 2023.

Board Justification

The amounts represent matching contributions made by us to the named executive officer’s 401(k) plan account.

Board Justification

This column reflects the aggregate grant date fair value of the applicable equity awards granted during the applicable year computed in accordance with ASC 718 for stock-based compensation transactions. Assumptions used in the calculation of these amounts are included in Note 7, 'Stock-Based Compensation' to our financial statements included in our Annual Report on Form 10-K for the year ended December 31, 2023.